Cat. No. |
Product Name |
Activity |
14.3.3 Proteins |
2145 |
Difopein |
High affinity inhibitor of 14.3.3 proteins; induces apoptosis |
2144 |
R18 |
Inhibitor of 14.3.3 proteins; induces apoptosis |
Bromodomains |
4650 |
I-BET 151 hydrochloride |
BET bromodomain inhibitor |
4499 |
(+)-JQ 1 |
Potent and selective BET bromodomain inhibitor |
4445 |
PFI 1 |
BET bromodomain inhibitor |
DNA Methyltransferases |
2624 |
Decitabine |
DNA methyltransferase inhibitor |
4359 |
Lomeguatrib |
MGMT inhibitor |
3295 |
RG 108 |
Non-nucleoside DNA methyltransferase inhibitor |
Histone Acetyltransferases |
3084 |
Anacardic acid |
Noncompetitive PCAF/p300 HAT inhibitor |
4200 |
C 646 |
Selective p300/CBP HAT inhibitor |
Histone Deacetylases |
4593 |
GSK J1 |
Potent histone demethylase JMJD3/UTX inhibitor |
4594 |
GSK J4 |
Histone demethylase JMJD3/UTX inhibitor; cell permeable |
4077 |
MC 1568 |
Selectively inhibits HDAC class II (IIa) |
3747 |
NCH 51 |
Histone deacetylase inhibitor |
4403 |
Pyroxamide |
Histone deacetylase inhibitor |
3810 |
SBHA |
Histone deacetylase inhibitor |
2682 |
Sodium 4-Phenylbutyrate |
Histone deacetylase inhibitor |
4270 |
TC-H 106 |
Class I histone deacetylase inhibitor |
3852 |
Tranylcypromine hydrochloride |
Irreversible inhibitor of MAO-A, MAO-B and LSD1 |
1406 |
Trichostatin A |
Histone deacetylase inhibitor |
3402 |
Tubacin |
HDAC 6 inhibitor; inhibits α-tubulin deacetylation |
Histone Methyltransferases |
3364 |
BIX 01294 |
G9a-like protein and G9a histone lysine methyltransferase inhibitor |
4504 |
Chaetocin |
Selective histone methyltransferase SUV39H1 inhibitor |
3861 |
UNC 0224 |
Potent G9a histone lysine methyltransferase inhibitor |
4343 |
UNC 0638 |
Selective G9a and GLP histone lysine methyltransferase inhibitor |
4342 |
UNC 0646 |
Potent and selective G9a/GLP inhibitor |
Hypoxia Inducible Factors |
4408 |
DMOG |
Prolylhydroxylase inhibitor |
4451 |
IOX 2 |
Potent, selective HIF1α prolyl hydroxylase-2 (PHD2) inhibitor |
JAK |
1571 |
Cucurbitacin I |
Selective inhibitor of STAT3/JAK2 signaling |
4338 |
NSC 33994 |
JAK2 inhibitor |
MBT Domains |
4666 |
UNC 1215 |
Potent and selective L3MBTL3 domain inhibitor |
4516 |
UNC 926 hydrochloride |
Binds the MBT domain of L3MBTL1 polycomb group protein |
Poly(ADP-ribose) Polymerase |
3735 |
BYK 49187 |
PARP-1 and PARP-2 inhibitor |
1401 |
NU 1025 |
Potent PARP inhibitor |
3255 |
PJ 34 hydrochloride |
Potent PARP inhibitor |
3748 |
XAV 939 |
Tankyrase inhibitor; inhibits Wnt signaling |
Protein Serine/Threonine Phosphatases |
1136 |
Okadaic acid |
Protein phosphatase 1 and 2A inhibitor |
2613 |
NSC 87877 |
Potent inhibitor of shp2 and shp1 PTP |