マニキュアの欠点を補ったシーリング剤

この製品に関するご意見・ご照会・お問合せはこちら

CoverGrip™ Coverslip Sealant

Nail polish belongs in the beauty salon, not in the lab... 

Traditionally, nail polish has been used to seal the edges of wet-mounted coverslips prior to fluorescence imaging.

Unfortunately, common ingredients in nail polish can leachinto aqueous mounting medium and ruin your specimen.

In addition, the strength and durability of sealing varies from brand to brand of nail polish.
Alternative sealants like wax and rubber cement aremessy and not durable

CoverGrip™ Coverslip Sealant is the only product designed specifically for sealing the edges of coverslips!

FEATURES

• First product designed specifically for sealing the edges of wetmounted coverslips

• Won’t leach into wet-set antifade mounting medium

• Dries to form a clear, durable hard seal around wet-mounted coverslips

• Made with d-limonene, a natural, environmentally friendly solvent with a pleasant citrus scent

• Supplied ready to use with a convenient brush applicator cap; refill bottles also available

この製品に関するご意見・ご照会・お問合せはこちら

ウェスタンブロッティング/免疫蛍光染色/免疫沈降/ChIPに使用可能

 この製品に関するご意見・ご照会・お問合せはこちら

Western Blot using Acetyl Lysine Antibody

Cytoskeleton's Anti-Acetyl Lysine Antibody Cat. # AAC01 recognizes 10 ng of chemically acetylated BSA and is comparable in sensitivity to other commercially available antibodies.  Unlike other Anti-Acetyle Lysine antibodies this antibody does not show cross reactivity with non-acetylated BSA.

Immunoprecipitation using Acetyl Lysine Antibody

Ability of AAC01 to IP histones was compared to other commercially available antibodies.  Cytoskeleton's Anti-Acetyl Lysine Antibody provides clear advantages for IP applications. Each tube is sufficient for approximately 20 IP assays.  

 

Immunofluorescence using Acetyl Lysine Antibody

ChIP using Acetyl Lysine Antibody

 この製品に関するご意見・ご照会・お問合せはこちら

Polysciences社では生分解性高分子を販売しています。各種ポリマーに加えて、均一サイズの粒子タイプもラインアップしています。生分解性高分子は、ドラッグデリバリーの担体、縫合糸やインプラントの材料、土壌中で分解するプラスチックなどの研究に有用です。

• Biodegradable Particles
• Poly(dl-lactide/glycolide) Polymers
• Poly(l-lactic acid) Polymers
• Polycaprolactone-Polyethylene Glycol Diblock Polymers
• Polycaprolactone-Polyethylene Glycol Triblock Polymers
• Polylactic Acid-Polyethylene Glycol Diblock Polymers
• Polylactic Acid-Polyethylene Glycol Triblock Polymers
• Other Polymers

※ 研究用ですので臨床用としては使用できません。

この製品に関するご意見・ご照会・お問合せはこちら

メーカー情報

Polysciences is pleased to offer a range of bio-erodable polymers for evaluation and product development. These materials find usefulness for studies involving bio-erodable drug matrices, biodegradable sutures and implant materials, as well as for situations requiring polymers which can biodegrade when placed in the soil.

 ● Biodegradable Particles   

Biodegradable polymers & microspheres such as PLGA types are receiving high levels of interest for controlled release of active materials in the pharmaceutical industry as growth platforms (e.g. degradable scaffolds for implants and bone grafts) and as prototype materials to measure biodegradation kinetics under specific conditions.

As these sciences expand, there will be a need for controlled particle size biodegradable microspheres for calibration of instrumentation and for particle size assays.

Polysciences Inc. offers two PLGA polymer (50:50 and 75:25 Lactic Acid : Glycolic Acid) in three narrow sizes (75μm, 100μm and 120μm; 5-10% CVs). These highly uniform particle populations serve as excellent models for controlled degradation rate measurements, and for the development of prototype scaffolds or devices.

• Poly(Lactic Acid-co-Glycolic Acid) Uniform Dry Microspheres, 50:50 LA/GA, 100µm
• Poly(Lactic Acid-co-Glycolic Acid) Uniform Dry Microspheres, 50:50 LA/GA, 120µm
• Poly(Lactic Acid-co-Glycolic Acid) Uniform Dry Microspheres, 50:50 LA/GA, 75µm
• Poly(Lactic Acid-co-Glycolic Acid) Uniform Dry Microspheres, 75:25 LA/GA, 100µm
• Poly(Lactic Acid-co-Glycolic Acid) Uniform Dry Microspheres, 75:25 LA/GA, 120μm
• Poly(Lactic Acid-co-Glycolic Acid) Uniform Dry Microspheres, 75:25 LA/GA, 75μm

 ● Poly(dl-lactide/glycolide) Polymers   

These copolymers are prepared for easier processability and for modified properties. Polysciences offers both l-lactide and dl-lactide copolymer in several ratios. Other ratios can be prepared on a custom basis. 

• Poly(d,l-lactide-co-glycolide), [75:25]
• Poly(dl-lactide/glycolide) [50:50] [MW ~ 12,000 - 16,000]
• Poly(dl-lactide/glycolide) [50:50] [MW ~ 150,000]
• Poly(dl-lactide/glycolide) [70:30]
• Poly(dl-lactide/glycolide) [80:20]
• Poly(dl-lactide/glycolide) [85:15]
• Poly(dl-lactide/glycolide) [90:10]

 ● Poly(l-lactic acid) Polymers   

This polymer has been widely used in sutures, implants and controlled release systems. It’s low molecular weights are for drug matrices, but its high molecular weights are for osteosynthesis (pins for bone repair). Poly(l-lactic acid) Kit (Cat. #18599) contains 5g each of 4 available polymers in the MW range of 2,000 to 300,000.

• Poly(l-lactic acid) [MW ~ 1,600 - 2,400] 
• Poly(l-lactic acid) [MW ~ 325,000 - 460,000]
• Poly(l-lactic acid) [MW ~ 700,000]
• Poly(l-lactic acid) [MW ~ 80,000 - 100,000]
• Poly(l-lactic acid) [MW 40-70 K]
• Poly(l-lactic acid) Molecular Weight Kit

 ● Polycaprolactone-Polyethylene Glycol Polymers   

There is increased interest in biodegradable polymers for both biomedical and industrial applications. Among the leading candidates for biodegradation are caprolactone based materials due to it's approved uses by the FDA for drug delivery systems, sutures, long term implants and adhesion barriers as well as new tissue scaffold host systems.

Caprolactone itself is a biodegradable polyester with a relatively low melting point (60C) but a glass transition temperature (Tg) around -60C. The high crystallinity in the polyester accounts for this property balance. It is made by metal catalyzed ring opening polymerization of epsilon caprolactone. A typical molecular weight of standard polycaprolactone homopolymer is 188k Daltons. By comparison, a 100% polylactic acid homopolymer with Mw 330k Daltons has a (Tg) temperature of +55C and a melting temperature, Tm of about 175C.

Further modifications of polycaprolactone are possible by converting it into diblock (A-B) or triblock (A-B-A) copolymers with polyethylene glycol. Synthetic methods which lead to block structures allow the polymer to have controlled biodegradation rates as well as improved physiological compatibility characteristics. Low molecular weight PEG blocks or caprolactone blocks are tolerated in the human body and are excretable. Such amphiphilic block copolymers are also convertible into polymersomes or vesicles which may contain active compounds (API) which are released during degradation.

ln addition to our full line of Polycaprolactone Diblock and Triblock Polymers, Polysciences, Inc. offers custom synthesis services for other compositions and block molecular weights. The numbers listed under the product indicate the approximate molecular weight of the block segments. The PEG terminal groups are blocked as methyl ethers but the caprolactone end groups are hydroxyl and are suitable for functionalization.

・Diblock Polymers

• PCL(1,000)-b-PEG(1,000), Diblock Polymer
• PCL(1,000)-b-PEG(2,000), Diblock Polymer
• PCL(1,000)-b-PEG(5,000), Diblock Polymer
• PCL(5,000)-b-PEG(1,000), Diblock Polymer
• PCL(5,000)-b-PEG(2,000), Diblock Polymer
• PCL(5,000)-b-PEG(5,000), Diblock Polymer

・Triblock Polymers

• PCL(1,000)-b-PEG(1,000)-b-PCL(1,000), Triblock Polymer
• PCL(1,000)-b-PEG(10,000)-b-PCL(1,000), Triblock Polymer
• PCL(1,000)-b-PEG(2,000)-b-PCL(1,000), Triblock Polymer
• PCL(1,000)-b-PEG(6,000)-b-PCL(1,000), Triblock Polymer
• PCL(5,000)-b-PEG(1,000)-b-PCL(5,000), Triblock Polymer
• PCL(5,000)-b-PEG(10,000)-b-PCL(5,000), Triblock Polymer
• PCL(5,000)-b-PEG(2,000)-b-PCL(5,000), Triblock Polymer
• PCL(5,000)-b-PEG(5,000)-b-PCL(5,000), Triblock Polymer

 ● Polylactic Acid-Polyethylene Glycol Polymers   

Biodegradable Polymers based on copolymers of polylactic acid (PLA) and polyethylene glycol (PEG) offer scientists new tools for controlled release formulations and delivery platforms.

Polymer structures featuring polyethylene glycol (PEG), with biodegradable or biocompatabile segments offering micelluar, nano and microsphere morphologies which are useful for controlled release formulations. Molecular weights of blocks controlled by GPC. Alternative structures can be synthesized.

A new class of polymeric biomaterials is emerging. The biodegradability of polymers based on lactic acid(LA) and its copolymers with ethylene glycol (EG) opens up new avenues for drug delivery, gene therapy, tissue engineering and determination of cellular pathway mechanisms.

Historically there have been three basic building block monomers for degradable polymers: lactides, glycolides and caprolactone. All are in clinical use and show varying degrees of degradability based on backbone compositions, crystallinity and molecular weights.

Lactic acid is a “chiral” molecule having both (L) and (D) forms with (L) being the common metabolite. The family of lactic acid polymers includes the pure poly-L- lactic acid (L form of PLA), the pure poly-D-lactic acid and the poly-D, L lactic acid (DL-PLA). Many other useful compositions occur when the polymer is organized into diblocks with ethylene glycol and/or glycolic acid comonomers or triblocks with ethylene glycol and/or glycolic acid.

Polymers of this type are insoluble in water but degrade by hydrolytic attack on their ester bonds. This degradation can be mediated by selective choice of comonomers such as ethylene glycol which enhance the penetration of water and rate of hydrolysis.

・Diblock Polymers

• PEG(1,000)-b-PLA(5,000), Diblock Polymer
• PEG(1,000)-b-PLA(750), Diblock Polymer
• PEG(10,000)-b-PLA(5,000), Diblock Polymer
• PEG(350)-b-PLA(300), Diblock Polymer
• PEG(5,000)-b-PLA(1,000), Diblock Polymer
• PEG(5,000)-b-PLA(10,000), Diblock Polymer
• PEG(5,000)-b-PLA(5,000), Diblock Polymer

・Triblock Polymers 

• PLA(1,000)-b-PEG(1,000)-b-PLA(1,000), Triblock Polymer
• PLA(1,000)-b-PEG(10,000)-b-PLA(1,000), Triblock Polymer
• PLA(1,000)-b-PEG(4,000)-b-PLA(1,000), Triblock Polymer
• PLA(10,000)-b-PEG(10,000)-b-PLA(10,000), Triblock Polymer
• PLA(2,000)-b-PEG(1,000)-b-PLA(2,000), Triblock Polymer
• PLA(5,000)-b-PEG(1,000)-b-PLA(5,000), Triblock Polymer
• PLA(5,000)-b-PEG(10,000)-b-PLA(5,000), Triblock Polymer

 ● Other Polymers   

• Biodegradable Polymers Kit
• Glycolide, 99.9%
• Guar Gum
• Poly(dimethylsiloxane-b-ethylene oxide), methyl terminated
• Poly(dimethylsiloxane-b-ethylene oxide), methyl terminated
• Poly(dl-lactic acid) [MW ~ 20,000 - 30,000]
• Poly(dl-lactic acid) [MW 15,000]
• Poly(dl-lactic acid) i.v. 2.0 -2.8dl/g
• Poly(ethylene oxide-b-propylene oxide)
• Poly(ethylene oxide-b-propylene oxide) [ratio 0.15:1]
• Poly(ethylene oxide-b-propylene oxide) [ratio 0.33:1]
• Poly(ethylene oxide-b-propylene oxide) [ratio 0.8:1]
• Poly(ethylene oxide-b-propylene oxide) [ratio 3:1]
• Poly(glycolic acid) [i.v. 1.0-2.0]
• Poly(l-alanine)
• Poly(l-lactide/glycolide) [70:30]
• Poly(l-lactide/glycolide) [70:30]
• Poly[(-)3-hydroxybutyric acid]
• Poly[(R)-3-hydroxybutyrate], MW ~ 10,000
• Poly[(R)-3-hydroxybutyrate], MW ~ 1000
• Poly[(R)-3-hydroxybutyrate], MW ~ 2000
• Poly[(R)-3-hydroxybutyrate], MW ~ 3000
• Poly[(R)-3-hydroxybutyrate], MW ~ 500
• Poly[(R)-3-hydroxybutyrate], MW ~ 5000
• Polycaprolactam [MW ~ 18,000]
• Polycaprolactam [MW 35,000]
• Polycaprolactone
• Polycaprolactone diol [MW 1,250]
• Polycaprolactone diol [MW 2,000]
• Polycaprolactone, powdered
• Polycaprolactone-based Biodegradable Polymers
• Polyethylene-co-vinyl acetate 70:30 (wt) MW 55,000
• Polyethylene-co-vinyl acetate 70:30 (wt) MW 60,000
• Polylactic Acid and Polyethylene Glycol Based Biodegradable Polymers
• Pullulan, desalinized

この製品に関するご意見・ご照会・お問合せはこちら

分子量制御が容易な重合剤
RAFT剤

RAFT（Reversible Addition Fragmentation chain Transfer）重合は、リビング重合の一種であり1998年CSIRO（Commonwealth Scientific and Industrial Research Organisation）にて発見された重合反応です。この重合反応は、狭い分子量分布で重合可能なことから注目されています。Strem社では、さまざまなモノマーに対応するRAFT剤を用意しています。 

特長

• 狭い分子量分布で重合可能
• さまざまなモノマーに対応するRAFT剤をご用意
• 複合構造（ブロック、グラフト、星型など）を有する共重合体の合成も可能

RAFT重合のメカニズム

RAFT重合では、一般的なラジカル重合の素反応（開始・成長・停止）に加えて下記のような速いRAFT平衡が起こります。重合生成物中に、チオカルボニルチオ基が生成されるために、副反応である不可逆的連鎖移動や停止反応が起こりにくく、狭い分子量範囲で重合可能です。このことにより、等量数など反応条件を調整することにより分子量制御した重合が可能となります。

モノマー適合表 

一般的なモノマーに対するRAFT剤との適合表です。スチレンやメタクリラートは各種RAFT剤に適しています。一方、ビニルエステルやビニルアミドは、適合するRAFT剤が限定されます。Strem社では各RAFT剤500mgから構成されるキット（#96-4700）も提供しています。

価格表

製品名	毒劇物	メーカー 製品番号	容量	価格	オンライン カタログへ
RAFT Agent Kit for controlling polymerizations at the molecular level	劇	96-4700	1 kit	118,500
2-Cyanomethyl-N-methyl-N-phenyldithiocarbamate, min. 97%	劇	16-0423	500 mg	14,400
S-Cyanomethyl-S-dodecyltrithiocarbonate, min. 97%	劇	16-0425	500 mg	16,500
2-Cyanoprop-2-yl-dithiobenzoate, min. 97%	劇	16-0430	500 mg	14,400
4-Cyano-4-(thiobenzoylthio)pentanoic Acid, min. 97%	劇	16-0422	500 mg	15,000
S-(2-Cyanoprop-2-yl)-S-dodecyltrithiocarbonate, min. 97%	劇	16-0610	500 mg	14,400
4-Cyano-4-(dodecylsulfanylthiocarbonyl)sulfanylpentanoic Acid, min. 97%	劇	16-0415	500 mg	16,500
2-Methyl-2-[(dodecylsulfanylthiocarbonyl)sulfanyl]propanoic Acid, min. 97%		16-0460	500 mg	14,400
S,S-Dibenzyltrithiocarbonate, min. 97%		16-0617	500 mg	14,400

※記載の内容は、'14年5月現在の情報に基づいております。

コンテンツ「国内研究者使用例」に情報を追加しました。

■ 今回追加の使用例

• StemCulture社　StemBeads FGF2　：　マウス神経前駆細胞の未分化維持培養での効果

国内研究者使用例　一覧へ

売れ筋色素のCF448A、CF568、CF594を対象として、CF™ Dye標識二次抗体（小容量サイズ）をディスカウントしてご提供します。是非、この機会にお試しください。

【期　　間】

2014年4月1日(火) ～ 2014年6月30日(月)

【内　　容】

対象製品から2種類以上ご注文で大幅ディスカウント

• 2種類購入　　 → 希望納入価格合計の40%off
• 3種類以上購入 → 希望納入価格合計の50%off

【対象製品】

CF488A／CF568／CF594 標識二次抗体

• お試し用として、15種類のCF™ Dye標識二次抗体を選定
• 小容量サイズ50 μl（2 mg/ml）

LifeSensors 社は、ユビキチン研究試薬の開発販売をしているアメリカのメーカーです。ラインアップとしてLifeSensors 社独自のユビキチン研究用試薬と、ユビキチン研究試薬より派生して開発された可溶性タンパク質発現システム（SUMO タグ発現システム）を取り揃えています。この度2014年日本語版カタログを発刊しました。まだお手元にカタログをお届けできていない場合は、弊社営業所または販売取扱店までご連絡ください。

Web siteからのご請求、PDF版ダウンロードはこちら

カタログ掲載内容

タンパク質発現システム

• 各生物種用の発現システム
• SUMO タグ使用文献

ユビキチン研究ツール

• ユビキチン精製・検出試薬
• E2、E3 結合アッセイキット
• 酵素（E1、E2、E3、イソペプチダーゼ）
• イソペプチダーゼ基質
• ユビキチン誘導体、ユビキチン鎖
• 阻害剤
• 抗体
• E3、E3 基質、DUB、DUB 基質マイクロアレイサービス
• プロテアソーム研究用試薬
• ユビキチンパスウェイノックダウン細胞株

マニキュアの欠点を補ったシーリング剤

この製品に関するご意見・ご照会・お問合せはこちら

CoverGrip™ Coverslip Sealant

Nail polish belongs in the beauty salon, not in the lab... 

Traditionally, nail polish has been used to seal the edges of wet-mounted coverslips prior to fluorescence imaging.

Unfortunately, common ingredients in nail polish can leachinto aqueous mounting medium and ruin your specimen.

In addition, the strength and durability of sealing varies from brand to brand of nail polish.
Alternative sealants like wax and rubber cement aremessy and not durable

CoverGrip™ Coverslip Sealant is the only product designed specifically for sealing the edges of coverslips!

FEATURES

• First product designed specifically for sealing the edges of wetmounted coverslips

• Won’t leach into wet-set antifade mounting medium

• Dries to form a clear, durable hard seal around wet-mounted coverslips

• Made with d-limonene, a natural, environmentally friendly solvent with a pleasant citrus scent

• Supplied ready to use with a convenient brush applicator cap; refill bottles also available

この製品に関するご意見・ご照会・お問合せはこちら

ウェスタンブロッティング/免疫蛍光染色/免疫沈降/ChIPに使用可能

 この製品に関するご意見・ご照会・お問合せはこちら

Western Blot using Acetyl Lysine Antibody

Cytoskeleton's Anti-Acetyl Lysine Antibody Cat. # AAC01 recognizes 10 ng of chemically acetylated BSA and is comparable in sensitivity to other commercially available antibodies.  Unlike other Anti-Acetyle Lysine antibodies this antibody does not show cross reactivity with non-acetylated BSA.

Immunoprecipitation using Acetyl Lysine Antibody

Ability of AAC01 to IP histones was compared to other commercially available antibodies.  Cytoskeleton's Anti-Acetyl Lysine Antibody provides clear advantages for IP applications. Each tube is sufficient for approximately 20 IP assays.  

 

Immunofluorescence using Acetyl Lysine Antibody

ChIP using Acetyl Lysine Antibody

 この製品に関するご意見・ご照会・お問合せはこちら

Polysciences社では生分解性高分子を販売しています。各種ポリマーに加えて、均一サイズの粒子タイプもラインアップしています。生分解性高分子は、ドラッグデリバリーの担体、縫合糸やインプラントの材料、土壌中で分解するプラスチックなどの研究に有用です。

• Biodegradable Particles
• Poly(dl-lactide/glycolide) Polymers
• Poly(l-lactic acid) Polymers
• Polycaprolactone-Polyethylene Glycol Diblock Polymers
• Polycaprolactone-Polyethylene Glycol Triblock Polymers
• Polylactic Acid-Polyethylene Glycol Diblock Polymers
• Polylactic Acid-Polyethylene Glycol Triblock Polymers
• Other Polymers

※ 研究用ですので臨床用としては使用できません。

この製品に関するご意見・ご照会・お問合せはこちら

メーカー情報

Polysciences is pleased to offer a range of bio-erodable polymers for evaluation and product development. These materials find usefulness for studies involving bio-erodable drug matrices, biodegradable sutures and implant materials, as well as for situations requiring polymers which can biodegrade when placed in the soil.

 ● Biodegradable Particles   

Biodegradable polymers & microspheres such as PLGA types are receiving high levels of interest for controlled release of active materials in the pharmaceutical industry as growth platforms (e.g. degradable scaffolds for implants and bone grafts) and as prototype materials to measure biodegradation kinetics under specific conditions.

As these sciences expand, there will be a need for controlled particle size biodegradable microspheres for calibration of instrumentation and for particle size assays.

Polysciences Inc. offers two PLGA polymer (50:50 and 75:25 Lactic Acid : Glycolic Acid) in three narrow sizes (75μm, 100μm and 120μm; 5-10% CVs). These highly uniform particle populations serve as excellent models for controlled degradation rate measurements, and for the development of prototype scaffolds or devices.

• Poly(Lactic Acid-co-Glycolic Acid) Uniform Dry Microspheres, 50:50 LA/GA, 100µm
• Poly(Lactic Acid-co-Glycolic Acid) Uniform Dry Microspheres, 50:50 LA/GA, 120µm
• Poly(Lactic Acid-co-Glycolic Acid) Uniform Dry Microspheres, 50:50 LA/GA, 75µm
• Poly(Lactic Acid-co-Glycolic Acid) Uniform Dry Microspheres, 75:25 LA/GA, 100µm
• Poly(Lactic Acid-co-Glycolic Acid) Uniform Dry Microspheres, 75:25 LA/GA, 120μm
• Poly(Lactic Acid-co-Glycolic Acid) Uniform Dry Microspheres, 75:25 LA/GA, 75μm

 ● Poly(dl-lactide/glycolide) Polymers   

These copolymers are prepared for easier processability and for modified properties. Polysciences offers both l-lactide and dl-lactide copolymer in several ratios. Other ratios can be prepared on a custom basis. 

• Poly(d,l-lactide-co-glycolide), [75:25]
• Poly(dl-lactide/glycolide) [50:50] [MW ~ 12,000 - 16,000]
• Poly(dl-lactide/glycolide) [50:50] [MW ~ 150,000]
• Poly(dl-lactide/glycolide) [70:30]
• Poly(dl-lactide/glycolide) [80:20]
• Poly(dl-lactide/glycolide) [85:15]
• Poly(dl-lactide/glycolide) [90:10]

 ● Poly(l-lactic acid) Polymers   

This polymer has been widely used in sutures, implants and controlled release systems. It’s low molecular weights are for drug matrices, but its high molecular weights are for osteosynthesis (pins for bone repair). Poly(l-lactic acid) Kit (Cat. #18599) contains 5g each of 4 available polymers in the MW range of 2,000 to 300,000.

• Poly(l-lactic acid) [MW ~ 1,600 - 2,400] 
• Poly(l-lactic acid) [MW ~ 325,000 - 460,000]
• Poly(l-lactic acid) [MW ~ 700,000]
• Poly(l-lactic acid) [MW ~ 80,000 - 100,000]
• Poly(l-lactic acid) [MW 40-70 K]
• Poly(l-lactic acid) Molecular Weight Kit

 ● Polycaprolactone-Polyethylene Glycol Polymers   

There is increased interest in biodegradable polymers for both biomedical and industrial applications. Among the leading candidates for biodegradation are caprolactone based materials due to it's approved uses by the FDA for drug delivery systems, sutures, long term implants and adhesion barriers as well as new tissue scaffold host systems.

Caprolactone itself is a biodegradable polyester with a relatively low melting point (60C) but a glass transition temperature (Tg) around -60C. The high crystallinity in the polyester accounts for this property balance. It is made by metal catalyzed ring opening polymerization of epsilon caprolactone. A typical molecular weight of standard polycaprolactone homopolymer is 188k Daltons. By comparison, a 100% polylactic acid homopolymer with Mw 330k Daltons has a (Tg) temperature of +55C and a melting temperature, Tm of about 175C.

Further modifications of polycaprolactone are possible by converting it into diblock (A-B) or triblock (A-B-A) copolymers with polyethylene glycol. Synthetic methods which lead to block structures allow the polymer to have controlled biodegradation rates as well as improved physiological compatibility characteristics. Low molecular weight PEG blocks or caprolactone blocks are tolerated in the human body and are excretable. Such amphiphilic block copolymers are also convertible into polymersomes or vesicles which may contain active compounds (API) which are released during degradation.

ln addition to our full line of Polycaprolactone Diblock and Triblock Polymers, Polysciences, Inc. offers custom synthesis services for other compositions and block molecular weights. The numbers listed under the product indicate the approximate molecular weight of the block segments. The PEG terminal groups are blocked as methyl ethers but the caprolactone end groups are hydroxyl and are suitable for functionalization.

・Diblock Polymers

• PCL(1,000)-b-PEG(1,000), Diblock Polymer
• PCL(1,000)-b-PEG(2,000), Diblock Polymer
• PCL(1,000)-b-PEG(5,000), Diblock Polymer
• PCL(5,000)-b-PEG(1,000), Diblock Polymer
• PCL(5,000)-b-PEG(2,000), Diblock Polymer
• PCL(5,000)-b-PEG(5,000), Diblock Polymer

・Triblock Polymers

• PCL(1,000)-b-PEG(1,000)-b-PCL(1,000), Triblock Polymer
• PCL(1,000)-b-PEG(10,000)-b-PCL(1,000), Triblock Polymer
• PCL(1,000)-b-PEG(2,000)-b-PCL(1,000), Triblock Polymer
• PCL(1,000)-b-PEG(6,000)-b-PCL(1,000), Triblock Polymer
• PCL(5,000)-b-PEG(1,000)-b-PCL(5,000), Triblock Polymer
• PCL(5,000)-b-PEG(10,000)-b-PCL(5,000), Triblock Polymer
• PCL(5,000)-b-PEG(2,000)-b-PCL(5,000), Triblock Polymer
• PCL(5,000)-b-PEG(5,000)-b-PCL(5,000), Triblock Polymer

 ● Polylactic Acid-Polyethylene Glycol Polymers   

Biodegradable Polymers based on copolymers of polylactic acid (PLA) and polyethylene glycol (PEG) offer scientists new tools for controlled release formulations and delivery platforms.

Polymer structures featuring polyethylene glycol (PEG), with biodegradable or biocompatabile segments offering micelluar, nano and microsphere morphologies which are useful for controlled release formulations. Molecular weights of blocks controlled by GPC. Alternative structures can be synthesized.

A new class of polymeric biomaterials is emerging. The biodegradability of polymers based on lactic acid(LA) and its copolymers with ethylene glycol (EG) opens up new avenues for drug delivery, gene therapy, tissue engineering and determination of cellular pathway mechanisms.

Historically there have been three basic building block monomers for degradable polymers: lactides, glycolides and caprolactone. All are in clinical use and show varying degrees of degradability based on backbone compositions, crystallinity and molecular weights.

Lactic acid is a “chiral” molecule having both (L) and (D) forms with (L) being the common metabolite. The family of lactic acid polymers includes the pure poly-L- lactic acid (L form of PLA), the pure poly-D-lactic acid and the poly-D, L lactic acid (DL-PLA). Many other useful compositions occur when the polymer is organized into diblocks with ethylene glycol and/or glycolic acid comonomers or triblocks with ethylene glycol and/or glycolic acid.

Polymers of this type are insoluble in water but degrade by hydrolytic attack on their ester bonds. This degradation can be mediated by selective choice of comonomers such as ethylene glycol which enhance the penetration of water and rate of hydrolysis.

・Diblock Polymers

• PEG(1,000)-b-PLA(5,000), Diblock Polymer
• PEG(1,000)-b-PLA(750), Diblock Polymer
• PEG(10,000)-b-PLA(5,000), Diblock Polymer
• PEG(350)-b-PLA(300), Diblock Polymer
• PEG(5,000)-b-PLA(1,000), Diblock Polymer
• PEG(5,000)-b-PLA(10,000), Diblock Polymer
• PEG(5,000)-b-PLA(5,000), Diblock Polymer

・Triblock Polymers 

• PLA(1,000)-b-PEG(1,000)-b-PLA(1,000), Triblock Polymer
• PLA(1,000)-b-PEG(10,000)-b-PLA(1,000), Triblock Polymer
• PLA(1,000)-b-PEG(4,000)-b-PLA(1,000), Triblock Polymer
• PLA(10,000)-b-PEG(10,000)-b-PLA(10,000), Triblock Polymer
• PLA(2,000)-b-PEG(1,000)-b-PLA(2,000), Triblock Polymer
• PLA(5,000)-b-PEG(1,000)-b-PLA(5,000), Triblock Polymer
• PLA(5,000)-b-PEG(10,000)-b-PLA(5,000), Triblock Polymer

 ● Other Polymers   

• Biodegradable Polymers Kit
• Glycolide, 99.9%
• Guar Gum
• Poly(dimethylsiloxane-b-ethylene oxide), methyl terminated
• Poly(dimethylsiloxane-b-ethylene oxide), methyl terminated
• Poly(dl-lactic acid) [MW ~ 20,000 - 30,000]
• Poly(dl-lactic acid) [MW 15,000]
• Poly(dl-lactic acid) i.v. 2.0 -2.8dl/g
• Poly(ethylene oxide-b-propylene oxide)
• Poly(ethylene oxide-b-propylene oxide) [ratio 0.15:1]
• Poly(ethylene oxide-b-propylene oxide) [ratio 0.33:1]
• Poly(ethylene oxide-b-propylene oxide) [ratio 0.8:1]
• Poly(ethylene oxide-b-propylene oxide) [ratio 3:1]
• Poly(glycolic acid) [i.v. 1.0-2.0]
• Poly(l-alanine)
• Poly(l-lactide/glycolide) [70:30]
• Poly(l-lactide/glycolide) [70:30]
• Poly[(-)3-hydroxybutyric acid]
• Poly[(R)-3-hydroxybutyrate], MW ~ 10,000
• Poly[(R)-3-hydroxybutyrate], MW ~ 1000
• Poly[(R)-3-hydroxybutyrate], MW ~ 2000
• Poly[(R)-3-hydroxybutyrate], MW ~ 3000
• Poly[(R)-3-hydroxybutyrate], MW ~ 500
• Poly[(R)-3-hydroxybutyrate], MW ~ 5000
• Polycaprolactam [MW ~ 18,000]
• Polycaprolactam [MW 35,000]
• Polycaprolactone
• Polycaprolactone diol [MW 1,250]
• Polycaprolactone diol [MW 2,000]
• Polycaprolactone, powdered
• Polycaprolactone-based Biodegradable Polymers
• Polyethylene-co-vinyl acetate 70:30 (wt) MW 55,000
• Polyethylene-co-vinyl acetate 70:30 (wt) MW 60,000
• Polylactic Acid and Polyethylene Glycol Based Biodegradable Polymers
• Pullulan, desalinized

この製品に関するご意見・ご照会・お問合せはこちら

初代培養細胞を開始するのに最適なキット

 この製品に関するご意見・ご照会・お問合せはこちら

PrimaCell™ kit is complete primary cell culture systems to guide you step-by-step culturing various tissue primary cells of avian, human, mouse and rat. Each PrimaCell™ system is customized for different types of Avian, Mouse, Rat and Human cells and consists of seven components.

Delivering Power & Control in Your Hands
Our PrimaCell™ Kits deliver the ultimate solution for isolating and culturing Primary Cells to give you maximum flexibility and control over your experiments . Our cutting-edge approach saves time and resources so that you can achieve your most ambitious goals faster.

Achieving Your Most Ambitious Goals Faster
Our patented protocol technology and optimized quality reagents give you the freedom to focus on discovering the next breakthrough in biomedical research. Our PrimaCell™ Kits include everything you need to successfully isolate and culture Primary cells from human, mouse, rat, and avian.

PrimaCell™ Kit Components

• Optimal Cell-Specific Tissue Dissociation System
• Tissue-Specific  Fibroblast Growth Inhibitors, FibrOut™
• PrimaCell™ Basal Culture Medium
• Growth Factor & Cytokine Supplements
• Highly Purified & Specially Treated Serum
• Proprietary Buffers & Solutions for Tissue Preparation
• Step-by-Step Protocol

 この製品に関するご意見・ご照会・お問合せはこちら

エネルギー関連研究試薬

Strem社ではエネルギー関連の試薬として、下記製品群を取り扱っています。今回はこの中の、太陽電池、水素貯蔵関連の製品の中から一部を紹介します。エネルギー関連の試薬をまとめたカタログも好評配布中です。

カタログのご請求はこちら（8ページ目に掲載しています）

概要

• 太陽電池（無機物、Quantum Dots、金ナノロッド、CANdots^®）
• 水素貯蔵（アミド、水素化ほう素、金属有機構造体、炭素材料など）
• エネルギー貯蓄（リチウム、金属酸化物、炭素材料）
• 燃料電池（触媒、触媒前駆体、触媒の修飾など）
• LED（CANdots^®）

価格表

太陽電池関連

製品名	毒劇物	CAS No.	メーカー 製品番号	容量	価格	オンライン カタログへ
Antimony(III) Telluride (99.96%-Sb)	劇	1327-50-0	51-1430	1 g	6,000
Cadmium Arsenide (99.999%-Cd) PURATREM	毒	12006-15-4	48-0150	5 g	17,100
Cadmium Selenide CANdot® Quantum Dot (CdSe core), 50μmol/L in hexane, 525nm peak emission	毒		48-1011	5 ml	25,500
Cadmium Selenide/Zinc Selenide/Zinc Sulfide CANdot® Quantum Dot (CdSe core/shell/shell), 50μmol/L in hexane, 550nm peak emission	毒		48-1063	1 ml	18,600
Gold Wire (99.99%) 1.4mm径		7440-57-5	79-0095	2 cm	42,000
Gold Wire (99.999%) 1.4mm径		7440-57-5	79-0085	2 cm	159,600
Gold Nanorods (Axial Diameter - 10 nm) (Wavelength 700 nm)		7440-57-5	79-6020	5 ml	23,100
Lithium Iodide, Anhydrous, min. 98%		10377-51-2	93-0382	25 g	19,900
Lithium Iodide Trihydrate, 99+%		7790-22-9	93-0381	50 g	22,200
Titanium(IV) Isopropoxide, min. 98%, 93-2216, contained in 50 ml Swagelok® Cylinder (96-1070) for CVD/ALD		546-68-9	98-4030	25 g	181,800

水素貯蔵関連

製品名	CAS No.	メーカー 製品番号	容量	価格	オンライン カタログへ
Bis(N,N'-dimethylpiperazine)tetra[copper(I) Iodide], 98% MOF	1401708-91-5	29-0550	500 mg	11,400
Graphene Nanoplatelets (6 - 8 nm thick x 5 microns wide)	7782-42-5	06-0210	25 g	13,500
1-Ethyl-2,3-dimethylimidazolium Tosylate, 98% [EDiMIM] [TOS]	783321-71-1	07-0535	5 g	33,000
1-Ethyl-3-methylimidazolium Bis(trifluoromethylsulfonyl)imide, 99% [EMIIm]	174899-82-2	07-0579	1 g	31,200
Lithium Amide, 95%	7782-89-0	93-0306	50 g	7,200
Lithium Borohydride, 95%	16949-15-8	93-0397	1 g	7,200
1,4-Phenylenediacetic Acid, 97%	7325-46-4	08-1165	1 g	6,000
Zinc 2-Methylimidazole MOF (ZIF-8)	59061-53-9	30-4015	1 g	12,000
Zirconium 1,4-Dicarboxybenzene MOF (UiO-66)	1072413-80-9	40-1105	500 mg	12,600

※記載の内容は、'14年5月現在の情報に基づいております。

Strem社では、有機合成で使用される金属触媒やリガンド、エネルギー関連試薬等を掲載したProduct Bookletを発行しています。弊社Web sitよりご請求いただけます。

ご請求はこちら（8~9ページ目に掲載されています）

Metal Catalysts for Organic Synthesis
Strem社商品の中から有機合成反応で使用される金属触媒をまとめたカタログです。

Phosphorus Ligands and Compounds
Strem社商品の中から有機合成に使用される触媒用のリガンドをまとめたカタログです。

Buchwald Ligands and Precatalysts
Buchwald Ligandをまとめた冊子です。Buchwaldは、一連の配位子を開発した著名な科学者であり、Buchwaldのグループが開発した一連の化合物がBuchwald Ligandと呼ばれています。カップリング反応に有用なリガンドです。

Materials for Energy Applications
エネルギー関連研究用試薬をまとめた冊子です。

MOCVD, CVD and ALD Precursors
膜を作成する原料の冊子で、MOCVD(有機金属気相成長法)、CVD(化学蒸着)、ALD(原子層堆積法)の紹介と、使用される試薬が掲載されています。

Other Ligands
有機合成用リガンドの冊子です。

目的タンパク質のN末端側に融合するベクターを新しく追加
pFUSEN-Fc：Fc融合タンパク質発現ベクター

イムノグロブリンのFcドメインは、IgG重鎖のCH2-CH3領域とヒンジ領域から構成されます。このFcドメインとの融合タンパク質は、目的タンパク質にさまざまな特長を付加します。好評の目的タンパク質のC末端側に融合する従来のベクターに、新しくＮ末端側に融合する製品が追加されました。

特長

• 目的タンパク質の安定性や可溶性を向上
• 血中半減期を向上
• エフェクター機能を持つタンパク質の作製も可能
• 変異型Fc融合タンパク質発現ベクターも提供
• Protein A/Gアフィニティー担体により簡単に精製可能

製品説明

pFUSEN-Fcは、分泌シグナル（IL2ss）、複合プロモーター（EF1 prom/HTLV 5'UTR）を持ち、その下流に、Fcドメイン、クローニングサイトを有します。pFUSENは、一過性および安定的に哺乳類細胞にトランスフェクションできます。
pFUSEN-Fc-Luciaは、分泌型ルシフェラーゼレポーター遺伝子がコードされており、融合タンパク質の発現を簡単に確認できます。

価格表

pFUSEN-Fcベクターは、Fcドメインのアイソタイプ、動物種、変異の有無により、複数の製品を用意しています。

各動物種由来Fc融合タンパク質発現ベクター

製品名	メーカー 製品番号	容量	価格	オンライン カタログへ
pFUSEN-hG1Fc	pfcn-hg1	20 μg	127,000
アイソタイプ：IgG1　　種：human　　エフェクター活性：ADCC+++, CDC+++
pFUSEN-hG2Fc	pfcn-hg2	20 μg	127,000
アイソタイプ：IgG2　　種：human　　エフェクター活性：ADCC+/-, CDC+
pFUSEN-mG2aFc	pfcn-mg2	20 μg	127,000
アイソタイプ：IgG2a　　種：mouse　　エフェクター活性：ADCC+++, CDC+++
pFUSEN-Lucia-hG1Fc	pfcn-lchg1	20 μg	127,000
アイソタイプ：IgG1　　種：human　　エフェクター活性：ADCC+++, CDC+++
pFUSEN-Lucia-mG2aFc	pfcn-lcmg2a	20 μg	127,000
アイソタイプ：IgG2a　　種：mouse　　エフェクター活性：ADCC+++, CDC+++
pFUSEN-Lucia-hG2Fc	pfcn-lchg2	20 μg	127,000
アイソタイプ：IgG2　　種：human　　エフェクター活性：ADCC+/-, CDC+

変異型Fc融合タンパク質発現ベクター

製品名	メーカー 製品番号	容量	価格	オンライン カタログへ
pFUSEN-hG1e2Fc	pfcn-hg1e2	20 μg	134,000
アイソタイプ：IgG1　　種：human　　性質：Increased half-life
pFUSEN-Lucia-hG1e2Fc	pfcn-lchg1e2	20 μg	134,000
アイソタイプ：IgG1　　種：human　　性質：Increased half-life

目的タンパク質のC末端側に付加する製品は、InvivoGen社Web site（http://www.invivogen.com/fc-fusions）にてご確認ください。

※記載の内容は、'14年4月現在の情報に基づいております。

TLR /NODの応答を迅速に評価
InvivoGen社　TLRアレイ

本製品は全血、末梢血単核球（PBMC）、初代培養細胞などの生体試料や研究対象の細胞について、TLRやNODの応答を評価できます。あらかじめプレート内にそれぞれのTLRやNODに対するアゴニストが、様々な濃度でコートされており、サンプルとなる試料や細胞をウェルに添加するだけで、簡単に評価できます。

特長

• 操作は迅速かつ簡便
• マルチとシングルアゴニストタイプを用意
• マルチタイプは優れたコストパフォーマンス

製品概要

以下にマルチアゴニストタイプについて、ウェルのレイアウトを示します。

使用例

■マルチアゴニストタイプを用いたヒトPBMCのサイトカインプロファイリング

アレイにPBMCを添加後、37℃、5% CO₂の条件下、24時間インキュベーションした後、ELISAによりサイトカイン（IL-1、IL-6、TNF-α）の分泌を測定し、PBMCのTLRおよびNODの応答を確認しました。

価格表

マルチアゴニストタイププレート（形状：96ウェルプレート）

製品名 コーティングされているアゴニスト	メーカー 製品番号	容量	価格	オンライン カタログへ
Multi-TLR Array™ 10種のTLRと2種のNODアゴニスト	tlrl-arr	1 plates	63,000
	tlrl-arr-5	5 plates	249,000

シングルアゴニストタイプテストストリップ（形状：8ウェルストリップ）

製品名 コーティングされているアゴニスト	メーカー 製品番号	容量	価格	オンライン カタログへ
TLR1/2 Test Strip Pam3CSK4（TLR1/2 アゴニスト）	tlrs-tlr12	2×6 strips	63,000
	tlrs-tlr12-5	10×6 strips	249,000
TLR2 Test Strip HKLM（TLR2 アゴニスト）	tlrs-tlr2	2×6 strips	63,000
	tlrs-tlr2-5	10×6 strips	249,000
TLR2/6 Test Strip FSL-1（TLR2/6 アゴニスト）	tlrs-tlr26	2×6 strips	63,000
	tlrs-tlr26-5	10×6 strips	249,000
TLR3 Test Strip Poly(I:C)（TLR3 アゴニスト）	tlrs-tlr3	2×6 strips	63,000
	tlrs-tlr3-5	10×6 strips	249,000
TLR4 Test Strip LPS-EB Ultrapure（TLR4 アゴニスト）	tlrs-tlr4	2×6 strips	63,000
	tlrs-tlr4-5	10×6 strips	249,000
TLR5 Test Strip FLA-ST Ultrapure（TLR5 アゴニスト）	tlrs-tlr5	2×6 strips	63,000
	tlrs-tlr5-5	10×6 strips	249,000
TLR7 Test Strip imiquimod（TLR7 アゴニスト）	tlrs-tlr7	2×6 strips	63,000
	tlrs-tlr7-5	10×6 strips	249,000
TLR7/8 Test Strip R848（TLR7/8 アゴニスト）	tlrs-tlr78	2×6 strips	63,000
	tlrs-tlr78-5	10×6 strips	249,000
TLR9 Test Strip 2006 ODN 2006（TLR9 アゴニスト）	tlrs-2006	2×6 strips	63,000
	tlrs-2006-5	10×6 strips	249,000
TLR9 Test Strip 2216 ODN 2216（TLR9 アゴニスト）	tlrs-2216	2×6 strips	63,000
	tlrs-2216-5	10×6 strips	249,000
NOD1 Test Strip C12-iE-DAP（NOD1アゴニスト）	tlrs-nod1	2×6 strips	63,000
	tlrs-nod1-5	10×6 strips	249,000
NOD2 Test Strip MDP（NOD2アゴニスト）	tlrs-nod2	2×6 strips	63,000
	tlrs-nod2-5	10×6 strips	249,000

※記載の内容は、'14年5月現在の情報に基づいております。

この製品に関するご意見・ご照会・お問合せはこちら

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

この製品に関するご意見・ご照会・お問合せはこちら

Santa Cruz社　モノクローナル抗体　2014年3月新製品

Santa Cruz社では、キナーゼとホスファターゼ、シグナル中間体、転写因子など様々な研究対象のモノクローナル抗体を新発売しました。

新製品一覧

容量：200μg/ml　　価格：51,000円

用途：Western Blotting, Immunoprecipitation, Immunofluorescence, ELISA

略号：Av=Avian（Bird）, Bov=Bovine（Cow）, Ca=Canine, Hs=Horse（Equine）, Hu=Human, Ms=Mouse, Por=Porcine（Pig, Swine）, Rt=Rat

製品名	交差性	抗原	アイソタイプ	メーカー製品番号	オンライン カタログへ
構造タンパク質
α Tubulin (A-6)	Ms, Rt, Hu, Hs, Ca, Bov, Por, Av	22-49 (Hu)	mouse IgG2b	sc-398103
γ-parvin (A-11)	Ms, Rt	1-141 (Ms)	mouse IgG2b	sc-398027
emerin (G-10)	Hu > Ms, Rt	186-223 (Hu)	mouse IgG2b	sc-398067
KIF2A (D-7)	Ms, Hu	86-121 (Hu)	mouse IgG2a	sc-398010
合成と分解
ALDH9A1 (F-6)	Hu	219-518 (Hu)	mouse IgG1	sc-398054
AOS-1 (H-9)	Ms, Rt, Hu	261-287 (Hu)	mouse IgG3	sc-398080
CYB5R3 (G-11)	Hu	1-60 (Hu)	mouse IgG2a	sc-398043
IDH3A (A-10)	Hu, Rt	71-120 (Hu)	mouse IgG1	sc-398021
IDH3G (C-8)	Hu, Hs, Ca, Bov, Por	119-156 (Hu)	mouse IgM	sc-398066
MOCS1 (G-6)	Ms, Hu	87-385 (Hu)	mouse IgG1	sc-398094
MTHFS (G-8)	Hu	1-203 (Hu)	mouse IgG1	sc-398056
NDUFA8 (C-6)	Hu	1-172 (Hu)	mouse IgG2a	sc-398097
NDUFA8 (E-3)	Hu	1-172 (Hu)	mouse IgG2b	sc-398098
ODC (E-6)	Ms, Rt, Hu, Por	243-272 (Hu)	mouse IgG1	sc-398116
PDE7A (B-11)	Ms, Rt, Hu	451-482 (Hu)	mouse IgG2a	sc-398031
pUb-R5 (F-6)	Hu, Hs, Ca, Bov, Por	1-300 (Hu)	mouse IgG2a	sc-398033
USP14 (F-4)	Hu, Ca	195-494 (Hu)	mouse IgG1	sc-398009
神経生物学
Gl Syn (E-2)	Ms, Rt, Hu, Hs, Ca, Bov, Por	281-312 (Hu)	mouse IgG3	sc-398017
Gl Syn (F-4)	Ms, Rt, Hu, Hs, Ca, Bov, Por	281-310 (Hu)	mouse IgG1	sc-398034
NALP14 (H-10)	Hu	108-153 (Hu)	mouse IgG1	sc-398068
Neuroglycan C (A-7)	Hu	181-276 (Hu)	mouse IgG2a	sc-398051
NIPA1 (E-4)	Ms, Rt, Hu	210-229 (Hu)	mouse IgM	sc-398041
Nociceptin (F-10)	Hu	1-176 (Hu)	mouse IgG1	sc-398073
Torsin3A (D-9)	Hu	207-234 (Hu)	mouse IgG1	sc-398045
輸送関連タンパク質
α-Adaptin 1 (C-5)	Ms, Rt, Hs, Ca, Bov, Por	954-977 (Ms)	mouse IgG2b	sc-398024
α-Adaptin 1 (F-9)	Ms, Rt, Hs, Ca, Bov, Por	952-977 (Ms)	mouse IgG1	sc-398016
COPA (H-3)	Hu	934-1233 (Hu)	mouse IgG2b	sc-398099
COPZ1 (B-12)	Ms, Rt, Hu, Hs, Ca, Bov, Por	128-159 (Hu)	mouse IgG3	sc-398081
Endophilin B2 (A-12)	Ms, Rt, Hu, Hs, Ca, Bov, Por	349-374 (Hu)	mouse IgM	sc-398040
NASP (E-2)	Hu	489-788 (Hu)	mouse IgG2a	sc-398102
キナーゼとホスファターゼ
CRIK (A-6)	Hu, Hs, Ca, Por	1293-1592 (Hu)	mouse IgG1	sc-398095
DGUOK (E-7)	Hu	191-277 (Hu)	mouse IgG2b	sc-398093
DGUOK (G-11)	Hu	191-277 (Hu)	mouse IgG1	sc-398101
ERK 5 (C-7)	Ms, Rt, Hu, Ca, Bov	671-698 (Hu)	mouse IgG1	sc-398015
GAP1-InsP4 BP (E-7)	Ms, Rt, Hu, Hs, Ca, Bov, Por, Av	104-129 (Hu)	mouse IgG1	sc-398127
LOK (D-6)	Hu	258-308 (Hu)	mouse IgG1	sc-398083
MEK kinase-2 (H-9)	Ms, Rt, Hu, Hs, Por	588-611 (Ms)	mouse IgG2b	sc-398091
PDPc (D-11)	Hu, Rt	1-156 (Hu)	mouse IgG1	sc-398117
STYX (D-12)	Hu	134-223 (Hu)	mouse IgG2b	sc-398023
YSK1 (E-7)	Hu	302-357 (Hu)	mouse IgG1	sc-398092
腫瘍抑制因子 / アポトーシス
ARC (G-4)	Ms, Rt, Hu	101-134 (Hu)	mouse IgG2b	sc-398121
RCAS1 (D-9)	Ms, Rt, Hu	124-159 (Hu)	mouse IgG2a	sc-398052
Rfp2 (A-2)	Ms, Rt, Hu	34-51 (Hu)	mouse IgG2a	sc-398129
XAF1 (B-5)	Hu	1-225 (Hu)	mouse IgG1	sc-398012
シグナル中間体
αB-crystallin (C-5)	Ms, Rt, Hu, Por	117-152 (Hu)	mouse IgG2a	sc-398079
4.1B (B-6)	Ms, Hu	654-810 (Ms)	mouse IgG2b	sc-398089
4.1B (F-11)	Ms	654-810 (Ms)	mouse IgG1	sc-398084
AIP2 (A-3)	Ms, Rt, Hu	30-57 (Hu)	mouse IgG2a	sc-398090
Ataxin-3 (A-7)	Ms, Hu	176-234 (Ms)	mouse IgG2b	sc-398114
cleaved Thrombin APII (B-7)	Rt	314-329 (Rt)	mouse IgG3	sc-398087
cleaved Thrombin APII (G-1)	Rt	317-326 (Rt)	mouse IgG2b	sc-398035
DPP10 (B-3)	Ms, Rt	155-182 (Ms)	mouse IgG1	sc-398108
FBXO2 (E-9)	Hu	205-252 (Hu)	mouse IgG1	sc-398111
FBXO44 (C-10)	Hu, Por	86-125 (Hu)	mouse IgG1	sc-398020
HPS-4 (A-6)	Ms, Hu	526-671 (Ms)	mouse IgG2b	sc-398070
Junctophilin-2 (B-6)	Ms, Rt, Hu	552-579 (Hu)	mouse IgG1	sc-398125
NRAMP 1 (D-9)	Ms, Rt, Hu, Hs, Ca, Bov	71-98 (Hu)	mouse IgG2b	sc-398036
NRAMP 1 (E-2)	Ms, Rt, Hu, Hs, Ca, Bov	68-99 (Hu)	mouse IgG3	sc-398077
ORP150 (C-9)	Ms, Rt, Hu	117-139 (Hu)	mouse IgG1	sc-398110
PITPα/β (B-9)	Hu, Ca, Por	1-270 (Hu)	mouse IgG1	sc-398050
RASAL1 (B-2)	Hu	62-118 (Hu)	mouse IgG1	sc-398025
RGS16 (F-9)	Ms, Rt, Hu	170-199 (Hu)	mouse IgG2a	sc-398120
ROD1 (C-1)	Ms, Rt, Hu, Hs, Ca, Por	252-287 (Hu)	mouse IgG2a	sc-398105
SPR (H-12)	Ms, Rt, Hu, Hs, Ca	191-214 (Hu)	mouse IgG2b	sc-398126
Teneurin-1 (B-1)	Ms, Hu, Por	26-135 (Hu)	mouse IgG2b	sc-398018
UMPS (A-9)	Hu	208-445 (Hu)	mouse IgG1	sc-398086
ZFAND2B (A-1)	Ms, Rt, Hu, Hs	129-152 (Hu)	mouse IgG3	sc-398078
ZFAND2B (F-2)	Ms, Rt, Hu, Hs	128-149 (Hu)	mouse IgM	sc-398044
細胞膜受容体
frizzled-1 (E-7)	Ms, Rt, Hu, Hs, Ca, Bov, Av	308-333 (Hu)	mouse IgM	sc-398082
MARCO (F-3)	Hu	198-247 (Hu)	mouse IgG2a	sc-398053
TaR (D-7)	Ms, Rt	181-247 (Ms)	mouse IgG3	sc-398096
転写因子
ADAR2 (C-2)	Hu	281-370 (Hu)	mouse IgG2a	sc-398122
Bcl-9 (B-4)	Hu	521-770 (Hu)	mouse IgG1	sc-398131
BTEB2 (A-5)	Ms, Rt, Hu, Hs, Por	338-369 (Hu)	mouse IgG2a	sc-398014
CSB (E-6)	Hu	30-59 (Hu)	mouse IgG2a	sc-398022
EEPD1 (A-5)	Hu	501-569 (Hu)	mouse IgG2a	sc-398028
EEPD1 (B-5)	Hu	501-569 (Hu)	mouse IgG1	sc-398019
FANK1 (E-5)	Ms, Hu	1-300 (Hu)	mouse IgG1	sc-398057
FANK1 (F-5)	Ms, Hu	1-300 (Hu)	mouse IgG2a	sc-398026
FOG-2 (H-5)	Ms, Hu	880-1126 (Ms)	mouse IgG1	sc-398011
Id2 (E-7)	Ms, Rt, Hu	105-134 (Ms)	mouse IgG2a	sc-398104
Jun B (G-9)	Hu	1-44 (Hu)	mouse IgG1	sc-398061
KLF17 (B-6)	Hu	178-199 (Hu)	mouse IgG2b	sc-398132
Liprin α1 (A-6)	Ms, Rt, Hu	522-541 (Hu)	mouse IgM	sc-398030
NAB2 (A-5)	Ms, Rt, Hu, Hs, Ca, Por	489-516 (Hu)	mouse IgG1	sc-398123
Nrl (A-6)	Ms, Rt, Hu, Bov	42-69 (Hu)	mouse IgG3	sc-398046
POLR2I (F-11)	Hu, Hs, Ca, Bov, Por	1-120 (Hu)	mouse IgG1	sc-398049
Rpp38 (A-2)	Hu	205-246 (Hu)	mouse IgG1	sc-398112
Rpp38 (B-6)	Hu	205-246 (Hu)	mouse IgG2b	sc-398113
SMYD3 (C-3)	Hu	249-428 (Hu)	mouse IgG2b	sc-398085
TAF II p43 (B-7)	Hu	40-310 (Hu)	mouse IgG2a	sc-398062
TAL1 (H-5)	Ms, Rt, Hu, Por	46-67 (Hu)	mouse IgG1	sc-398124
XPF (F-11)	Ms, Rt, Hu	888-911 (Ms)	mouse IgG2a	sc-398032
ZFAT (E-9)	Hu	16-290 (Hu)	mouse IgG1	sc-398058
成長因子とホルモン
β-taxilin (E-5)	Ms, Rt	643-678 (Ms)	mouse IgG1	sc-398059
HAI-2 (H-9)	Ms, Rt	101-134 (Ms)	mouse IgG1	sc-398119
INSL5 (G-12)	Ms	1-135 (Ms)	mouse IgG1	sc-398048
LECT2 (A-7)	Ms, Rt, Hu	48-75 (Hu)	mouse IgG2b	sc-398072
LECT2 (B-6)	Ms, Rt, Hu	48-75 (Hu)	mouse IgG1	sc-398071
MIP-5 (A-12)	Hu	81-112 (Hu)	mouse IgM	sc-398069
リンパ球シグナル伝達
elafin (H-2)	Hu	1-117 (Hu)	mouse IgG2a	sc-398075
Lambda 5 (G-12)	Ms, Rt	31-56 (Ms)	mouse IgG1	sc-398037
NT5DC1 (G-6)	Hu	277-364 (Hu)	mouse IgG1	sc-398055
SH2D1A (A-8)	Ms, Hu	1-128 (Hu)	mouse IgG1	sc-398118
Siglec-1 (B-1)	Hu	42-97 (Hu)	mouse IgG1	sc-398109
GDP / GTP結合タンパク質
BIG2 (H-6)	Hu	585-636 (Hu)	mouse IgG2a	sc-398042
Mog1p (F-8)	Ms, Hu	11-88 (Hu)	mouse IgG2a	sc-398128
ホメオドメインタンパク質
Emx1 (G-6)	Hu	1-50 (Hu)	mouse IgG1	sc-398115
細胞接着タンパク質
α-actinin-4 (D-3)	Ms, Rt, Hu, Ca, Bov, Por	495-522 (Hu)	mouse IgM	sc-398088
COL9A2 (H-8)	Ms, Hu	341-515 (Hu)	mouse IgG1	sc-398130
connexin 36 (H-9)	Ms, Rt, Hu, Hs, Ca, Bov, Por	286-321 (Hu)	mouse IgG2a	sc-398063
Enigma (H-12)	Hu	184-293 (Hu)	mouse IgG1	sc-398100
M-cadherin (C-8)	Ms, Rt, Hu	710-727 (Hu)	mouse IgG2b	sc-398107
チャネルタンパク質
KCNC3 (D-4)	Ms, Rt, Hu, Bov, Por	709-724 (Hu)	mouse IgG2a	sc-398047
PMCA2/3 (C-3)	Ms, Hu, Hs, Ca, Bov, Por	83-194 (Hu)	mouse IgG2a	sc-398013
ステロイド受容体
RARγ (H-6)	Hu	417-454 (Hu)	mouse IgG1	sc-398065
その他
FLJ22184 (D-3)	Hu	40-69 (Hu)	mouse IgG2b	sc-398064
SCYL3 (E-7)	Ms, Rt, Hu, Hs, Ca, Bov, Por	70-95 (Hu)	mouse IgG1	sc-398106
Amino acid-binding ABC transporter (B-6)	Streptococcus equi subsp. equi 4047	1-278 (Streptococcus equi subsp. equi 4047)	mouse IgG1	sc-398076
cell surface-anchored protein (G-4)	Streptococcus equi subsp. equi 4047	294-494 (Streptococcus equi subsp. equi 4047)	mouse IgG2a	sc-398060
Endoglycosidase (EndoS) (B-8)	Streptococcus equi subsp. equi 4047	1-243 (Streptococcus equi subsp. equi 4047)	mouse IgG1	sc-398039
Extracellular solute-binding protein (B-6)	Streptococcus equi subsp. equi 4047	1-481 (Streptococcus equi subsp. equi 4047)	mouse IgG1	sc-398038
Extracellular solute-binding protein (E-11)	Streptococcus equi subsp. equi 4047	1-288 (Streptococcus equi subsp. equi 4047)	mouse IgG2b	sc-398029
Phosphate ABC transporter substrate-binding protein (A-10)	Streptococcus equi subsp. equi 4047	1-288 (Streptococcus equi subsp. equi 4047)	mouse IgG1	sc-398074

※記載の内容は、'14年4月現在の情報に基づいております。

細胞剥離液 Accutase™

Accutase™はready to useの細胞剥離液です。温和かつ迅速に作用するため、ES細胞や神経幹細胞などの幹細胞の剥離にも幅広く使用されています。

特長

• 温和かつ迅速な接着細胞の剥離が可能
• 哺乳動物やバクテリア由来成分不含
• 血清や阻害剤による中和が不要
• ほとんどのエピトープが保存されるためフローサイトメトリーに有用

実施例 

■ ヒト線維肉腫MG63細胞を用いたAccutase™処理効果の測定

DMEM ＋ 10% FBSで培養したヒト線維肉腫MG63細胞をAccutase™処理したところ、単一細胞の懸濁液として迅速に剥離され、かつ高い生存率がみられました。Accutase™で45分処理した後でもなお97 ± 3%の生存率があり、Accutase™は細胞に対して温和に作用することがわかりました。

使用実績

価格表

製品名	規格	貯法	製品番号	容量	価格
Accutase™	SP	冷凍	12679-54	100 ml

※記載の内容は、'14年5月現在の情報に基づいております。